benzyl 4-(methanesulfonyloxy)piperidine-1-carboxylate

benzyl 4-(methanesulfonyloxy)piperidine-1-carboxylate - Names and Identifiers

Name	1-((BENZYLOXY)CARBONYL)PIPERIDIN-4-YL METHANESULFONATE
Synonyms	1-Cbz-4-(mesyloxy)piperidine benzyl 4-(methanesulfonyloxy)piperidine-1-carboxylate 1-((BENZYLOXY)CARBONYL)PIPERIDIN-4-YL METHANESULFONATE 1-Piperidinecarboxylic acid, 4-[(Methylsulfonyl)oxy]-, phenylMethyl ester
CAS	199103-19-0

benzyl 4-(methanesulfonyloxy)piperidine-1-carboxylate - Physico-chemical Properties

Molecular Formula	C14H19NO5S
Molar Mass	313.36936
Density	1.31±0.1 g/cm3(Predicted)
Boling Point	492.3±44.0 °C(Predicted)
pKa	-3.07±0.40(Predicted)
Storage Condition	2-8°C
Use	Uses N-CBZ-4-methanesulfonyloxypiperidine is used as an intermediate for the preparation of conformation-limited saturated azacyclic sulfonyl chloride.

benzyl 4-(methanesulfonyloxy)piperidine-1-carboxylate - Introduction

1-((BENZYLOXY)CARBONYL)PIPERIDIN-4-YL methanosulfonate is an organic compound with the chemical structure 1-((BENZYLOXY)CARBONYL)PIPERIDIN-4-YL methanosulfonate.

Properties: 1-((BENZYLOXY)CARBONYL)PIPERIDIN-4-YL METHANESULFONATE is a white crystalline solid with a high melting point and relative molecular mass. It has good solubility at room temperature, soluble in ethanol and Ether solvents.

Purpose: 1-((BENZYLOXY)CARBONYL)PIPERIDIN-4-YL METHANESULFONATE is an important intermediate in organic synthesis. It can be used as a protecting group to protect sensitive functional groups in the synthesis and avoid unnecessary reactions. In addition, it can also be used in the preparation of other organic compounds, such as the synthesis of drugs and pesticides.

preparation method: the preparation of 1-((BENZYLOXY)CARBONYL)PIPERIDIN-4-YL methanesulfonfonate can be obtained by reacting N-methanesulfonylpiperidine with benzyl bromide. First, N-methanesulfonylpiperidine is reacted with benzyl bromoformate under basic conditions to give the target product, 1-((BENZYLOXY)CARBONYL)PIPERIDIN-4-YL METHANESULFONATE.

Safety information: 1-((BENZYLOXY)CARBONYL)PIPERIDIN-4-YL METHANESULFONATE is a relatively safe compound under general operating conditions. However, as a compound in organic synthesis, attention should be paid to its irritation to eyes and skin. Wear appropriate personal protective equipment at the time of use and operate in well-ventilated conditions.

Last Update：2024-04-09 20:45:29